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A US court just put ownership of CRISPR back in play

Antonio Regalado

created: May 13, 2025, 8 a.m. | updated: May 16, 2025, 9:12 a.m.

The pair shared a 2020 Nobel Prize for developing the versatile gene-editing system, which is already being used to treat various genetic disorders, including sickle cell disease. The new decision is a boost for the Nobelists, who had previously faced a string of demoralizing reversals over the patent rights in both the US and Europe. In 2012, Doudna and Charpentier were first to publish a description of a CRISPR gene editor that could be programmed to precisely cut DNA in a test tube. However, the patent fight relates to the use of CRISPR to edit inside animal cells—like those of human beings. That’s considered a distinct invention, and one both sides say they were first to come up with that very same year.

1 month, 1 week ago: MIT Technology Review