
Ultra-Powerful CRISPR Treatment Trialled in a Person
Saul Zimet
created: May 22, 2025, 1:31 p.m. | updated: May 22, 2025, 7:58 p.m.
“The CRISPR family’s most versatile member has made its medical debut: a cutting-edge gene-editing technique known as prime editing has been used to treat a person for the first time.
The recipient is a teenager with a rare immune disorder.
Researchers designed the treatment to correct a mutation that causes chronic granulomatous disease, a dangerous condition that disables a variety of immune cells, including those called neutrophils.
A month after the teenager received the treatment, he had experienced no serious side effects.
And the therapy seemed to have restored the function of a crucial enzyme in two-thirds of his neutrophils — more than enough to provide a significant boost to his immune system.”From Nature.
1 month, 4 weeks ago: HumanProgress