Photograph: Sleepsteady Sleepsteady Tencel Mattress Protector $84 AmazonMattress Protector: A Little ProtectionA mattress protector acts very similar to a fitted sheet. Getting a waterproof mattress protector is key, especially if you are dealing with spills, accidents, general clumsiness (@ me, spilling my nightcap Baja Blast in bed). Courtesy of Amazon Utopia Bedding Zippered Mattress Encasement $25 AmazonMattress Encasement: A Lot of ProtectionI’ve seen plenty of mattress encasements in use at hotels, Airbnbs, VRBOs, or just in the homes of very cautious people. Just like it sounds, a mattress encasement completely covers every inch of the mattress, kind of like a material force field or bubble. This protection will keep out the worst of the worst mattress offenders, like mildew, mold, and the dreaded bed bug.