The best mosquito repellents, from sprays to zappers, offer solid protection without interrupting your outdoor enjoyment. The Best Mosquito RepellentsBest Overall:Best for Large Spaces:Best for Hiking:Best for Small Spaces:Most Powerful:What To ConsiderChemicalsMost mosquito repellents use one of three active ingredients to protect you from bites: DEET, permethrin, or picaridin. Permethrin, on the other hand, is best used on clothing rather than directly on your skin. Tabletop vs. TopicalSprayable mosquito repellents move with you, while devices like zappers and candles stay in one place. How We SelectedTo find the best mosquito repellents, I first and foremost referenced my extensive personal experience.