Open Extended ReactionsAccording to ESPN BET, there are currently 21 teams with at least +10,000 odds (equivalent to about a 1% chance) of winning the national title in 2025. And now he enters 2025 as the Heisman betting favorite (+600), leading a team that is the national title co-favorite (+550) and the likely preseason No. CJ Carr, Notre Dame: Notre Dame made the national title game last season despite an offense focused mainly on short passes and lots of third-down QB keepers. Can he boost the Irish's upside enough to maybe actually win the national title game (while providing enough of a floor to get them back there)? The past eight national title quarterbacks averaged at least 13.6.