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Scientists Say They’ve Figured Out a Way to Reprogram the Pancreas to Produce GLP-1s Without Ozempic

Victor Tangermann

created: Nov. 9, 2025, 4:15 p.m. | updated: Nov. 19, 2025, 3:33 p.m.

Scientists say they’ve come up with a way for the body to produce its own store of glucagon-like peptide-1 (GLP-1). The idea is to coax existing cells into producing the hormone, reaping the benefits of GLP-1 drugs without ongoing treatment. Promisingly, obesity rates have also started to decline since 2022, with experts suspicious that GLP-1 drugs have contributed to the trend. Normal-weight mice also didn’t gain any weight and maintained healthy blood sugar levels after being treated and given a high-fat diet. More on GLP-1s: Trump Strikes Deal to Offer Americans GLP-1 Drugs for Much Cheaper

3 months ago: Futurism