That’s why you have celebrities like Oprah, who told People Magazine last month that she plans to stay on it indefinitely. “I’m on high blood pressure medication, and if I go off the high blood pressure medication, my blood pressure is going to go up. Physician Hussain Al-Zubaidi told the BBC that he’s seen patients gain 60 to 80 percent back of the weight they lost. That’s what happened to Ellen Ogley, who told the BBC that she lost 48.5 pounds while on Eli Lily’s GLP-1 drug Mounjaro. “I want people to know that life after Mounjaro can be sustainable as well,” she said.