Most recently, Hoffman has emerged as one of Silicon Valley’s most prominent defenders of artificial intelligence. In our conversation for this week’s episode of The Big Interview, Hoffman readily riffed on AI’s utility for pretty much everything, whether you’re looking for a research assistant or a second opinion on your blood work. Hoffman even relied on AI to make one of the most unconventional—and perhaps uncomfortable, depending on your view of AI-generated creativity—Christmas gifts I’ve heard of lately. (In 2019, Hoffman apologized for his mid-2010s relationship with Epstein, which he says related solely to fundraising for MIT. I mean, the people I would want to run for president probably won't.