Measles cases in the United States reached their highest level in more than 30 years in 2025, with 2,242 confirmed infections. A particularly bad outbreak in West Texas that began in January of last year was a significant driver of those cases. Now, a surge of measles in South Carolina is on track to outpace the West Texas outbreak, which could mean another year of high measles cases. The outbreak in South Carolina began last fall, when the state’s health department reported an initial eight measles cases on October 2. The West Texas measles outbreak resulted in 762 confirmed cases with 99 hospitalizations and two deaths among school-age children, both of whom were unvaccinated.